Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197837 | 0.84 | POLB (0.56) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL30211256 | 0.79 | POLB (0.46) | POLBMAPTKDM4EGAAADORA3 | |
| SCHEMBL7946300 | 0.79 | PDCD1 (0.40) | MAPTHTTKDM4EALDH1A1DHODH | |
| SCHEMBL23197838 | 0.79 | POLB (0.50) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL752046 | 0.75 | POLB (0.53) | POLBMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL28674515 | 0.74 | PLK1 (0.44) | POLBMAPTHTTKDM4EGAA | |
| SCHEMBL23197722 | 0.73 | POLB (0.63) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL17921816 | 0.73 | POLB (0.50) | POLBMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL23999688 | 0.73 | POLB (0.68) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL16098313 | 0.72 | TACR3 (0.73) | DHODHTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |