Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197837 | 0.82 | POLB (0.56) | POLBMAPTKDM4EGLAMEN1 | |
| SCHEMBL8569894 | 0.79 | POLB (0.51) | POLBMAPTKDM4EGLAMEN1 | |
| SCHEMBL23535319 | 0.75 | HPGDS (0.49) | POLBHPGDSMAPTKDM4EMEN1 | |
| SCHEMBL23204088 | 0.74 | GSK3B (0.36) | HPGDSMAPTMEN1KMT2A | |
| SCHEMBL753481 | 0.73 | POLB (0.51) | POLBMAPTKDM4EGLAMEN1 | |
| SCHEMBL14734375 | 0.72 | MAPT (0.47) | MAPTKDM4EHTTPDE10APTPN1 | |
| SCHEMBL23197722 | 0.72 | POLB (0.63) | POLBMAPTKDM4EGLAMEN1 | |
| SCHEMBL23999688 | 0.72 | POLB (0.68) | POLBMAPTKDM4EGLAMEN1 | |
| SCHEMBL752046 | 0.71 | POLB (0.53) | POLBMAPTKDM4EALOX15GAA | |
| SCHEMBL4272933 | 0.71 | POLB (0.66) | POLBMAPTKDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021063915-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021063914-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-04-08 | — | — | WO | disclosed |