SCHEMBL752046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17921816	0.89	POLB (0.50)	POLBMAPTALDH1A1GAAADORA3
	SCHEMBL753481	0.78	POLB (0.51)	POLBMAPTALDH1A1GAAKDM4E
	SCHEMBL16925510	0.76	ALDH1A1 (0.52)	POLBMAPTALDH1A1GAAKDM4E
	SCHEMBL8569894	0.75	POLB (0.51)	POLBMAPTALDH1A1GAAADORA3
	SCHEMBL752001	0.75	ALDH1A1 (0.50)	POLBMAPTALDH1A1GAAADORA3
	SCHEMBL23197837	0.73	POLB (0.56)	POLBMAPTALDH1A1GAAKDM4E
	SCHEMBL5172356	0.73	GAA (0.49)	MAPTALDH1A1GAATACR3
	SCHEMBL2073956	0.72	ALOX15 (0.71)	MAPTALDH1A1GAAALOX15
	SCHEMBL1332816	0.72	POLB (0.50)	POLBMAPTALDH1A1GAAADORA3
	SCHEMBL23197838	0.71	POLB (0.50)	POLBMAPTGAAKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.