Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572382 | 0.95 | ABL1 (0.36) | ABL1RAD52RIN1BRD4CCNT1 | |
| SCHEMBL8575388 | 0.80 | PTGS1 (0.44) | ABL1RAD52RIN1BRD4KDM4E | |
| SCHEMBL8571927 | 0.77 | ABL1 (0.38) | ABL1RAD52RIN1BRD4KDM4E | |
| SCHEMBL8575497 | 0.76 | PDE4A (0.41) | CHRM4AGTR2HPGD | |
| SCHEMBL8571045 | 0.75 | ABL1 (0.42) | ABL1RAD52RIN1BRD4ALDH1A1 | |
| SCHEMBL14862759 | 0.73 | KMT2A (0.45) | CHRM4ALDH1A1HPGD | |
| SCHEMBL8574158 | 0.72 | CPA1 (0.44) | ABL1RAD52RIN1KDM4EALDH1A1 | |
| SCHEMBL8569979 | 0.71 | SMN1; SMN2 (0.41) | ABL1RAD52RIN1BRD4KDM4E | |
| SCHEMBL8571555 | 0.71 | BRD4 (0.37) | ABL1RAD52RIN1BRD4ALDH1A1 | |
| SCHEMBL8571587 | 0.71 | GAA (0.39) | ABL1RAD52RIN1BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |