Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571587 | 0.91 | GAA (0.39) | SMN1; SMN2POLBLMNACYP1A2ABL1 | |
| SCHEMBL8571555 | 0.86 | BRD4 (0.37) | LMNAABL1RAD52RIN1BRD4 | |
| SCHEMBL2524514 | 0.85 | TSHR (0.39) | SMN1; SMN2POLBCYP1A2KDM4EABL1 | |
| SCHEMBL8574158 | 0.85 | CPA1 (0.44) | KDM4EABL1RAD52RIN1 | |
| SCHEMBL8575582 | 0.83 | TAS1R3 (0.40) | SMN1; SMN2POLBLMNAABL1RAD52 | |
| SCHEMBL8575388 | 0.79 | PTGS1 (0.44) | CYP1A2KDM4EABL1RAD52RIN1 | |
| SCHEMBL8571045 | 0.79 | ABL1 (0.42) | POLBLMNACYP1A2ABL1RAD52 | |
| SCHEMBL8572893 | 0.79 | LDHA (0.46) | POLBBRD4L3MBTL1 | |
| SCHEMBL8575109 | 0.78 | MMP1 (0.39) | POLBKMT2A | |
| SCHEMBL8571927 | 0.76 | ABL1 (0.38) | CYP1A2KDM4EABL1RAD52RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |