Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571927 | 0.88 | ABL1 (0.38) | PTGS1PTGS2ABL1RAD52RIN1 | |
| SCHEMBL8571045 | 0.83 | ABL1 (0.42) | PTGS1PTGS2ABL1RAD52RIN1 | |
| SCHEMBL8572382 | 0.82 | ABL1 (0.36) | ABL1RAD52RIN1BRD4KMT2A | |
| SCHEMBL8569996 | 0.80 | TTK (0.35) | ABL1RAD52RIN1BRD4KDM4E | |
| SCHEMBL8574158 | 0.80 | CPA1 (0.44) | ABL1RAD52RIN1KDM4EALDH1A1 | |
| SCHEMBL8569979 | 0.79 | SMN1; SMN2 (0.41) | ABL1RAD52RIN1BRD4KMT2A | |
| SCHEMBL8571555 | 0.79 | BRD4 (0.37) | PTGS1ABL1RAD52RIN1BRD4 | |
| SCHEMBL8571587 | 0.79 | GAA (0.39) | ABL1RAD52RIN1BRD4ALDH1A1 | |
| SCHEMBL8575582 | 0.78 | TAS1R3 (0.40) | ABL1RAD52RIN1KMT2AALDH1A1 | |
| SCHEMBL2524514 | 0.78 | TSHR (0.39) | ABL1RAD52RIN1BRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |