Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147722 | 0.74 | HSD17B3 (0.51) | CA9MAOALMNAMEN1MAPT | |
| SCHEMBL8108546 | 0.71 | CA12 (0.55) | CA12CA9MAOAMAOBLMNA | |
| SCHEMBL1095047 | 0.71 | HSD17B3 (0.44) | CA9MAOAMEN1MAPTKMT2A | |
| SCHEMBL7115025 | 0.70 | MAOB (0.48) | CA12CA9MAOAMAOBNPC1 | |
| SCHEMBL9695853 | 0.65 | ADORA3 (0.47) | MAOAMAOBLMNANPC1MEN1 | |
| SCHEMBL5326900 | 0.64 | ALDH1A1 (0.60) | LMNAERAP1NPC1MEN1MAPT | |
| SCHEMBL6584683 | 0.64 | KDM4E (0.71) | MAOBLMNAERAP1MEN1MAPT | |
| SCHEMBL28226496 | 0.64 | PTPRS (0.71) | ARNPC1MEN1MAPTKMT2A | |
| SCHEMBL1513142 | 0.64 | APP (0.50) | CA12CA9LMNAMAPTALDH1A1 | |
| SCHEMBL27586405 | 0.64 | AR (0.62) | CA12CA9MAOAARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |