Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571552 | 0.94 | SCN5A (0.42) | SCN5AKCNH2 | |
| SCHEMBL8566096 | 0.94 | SCN5A (0.42) | SCN5AKCNH2 | |
| Hydrochloric Acid SCHEMBL8574033 | 0.94 | SCN5A (0.42) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8561605 | 0.94 | SCN5A (0.42) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL8567585 | 0.92 | KCNH2 (0.43) | SCN5AKCNH2KDM4EALDH1A1 | |
| SCHEMBL8563854 | 0.92 | SCN5A (0.38) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7494375 | 0.91 | KCNH2 (0.42) | SCN5AKCNH2KDM4EALDH1A1 | |
| SCHEMBL8566850 | 0.88 | ALDH1A1 (0.46) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL8562588 | 0.88 | ALDH1A1 (0.46) | SCN5AKCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL14515902 | 0.88 | SCN5A (0.40) | SCN5AKCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |