Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31168096 | 0.84 | ABL1 (0.47) | PPARGPPARDPPARAALDH1A1EPHX2 | |
| SCHEMBL29858917 | 0.83 | P2RX1 (0.51) | SLC6A2SLC6A4ALDH1A1JAK2JAK1 | |
| SCHEMBL966871 | 0.82 | RXRB (0.50) | PPARGPPARDPPARAALDH1A1EPHX2 | |
| SCHEMBL14968582 | 0.81 | SCN9A (0.53) | SLC6A2SLC6A4ALDH1A1JAK2JAK1 | |
| SCHEMBL4666472 | 0.81 | FFAR4 (0.44) | PPARGPPARDPPARAEPHX2NR1H4 | |
| SCHEMBL965069 | 0.81 | CHEK1 (0.46) | PPARGPPARDPPARASLC6A2SLC6A4 | |
| SCHEMBL4767061 | 0.80 | PLK1 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7999913 | 0.79 | CHEK1 (0.45) | PPARGPPARDPPARASLC6A2SLC6A4 | |
| SCHEMBL2208745 | 0.78 | HPGD (0.63) | SLC6A2SLC6A4EPHX2NR1H4TRPV1 | |
| SCHEMBL20188661 | 0.78 | POLB (0.50) | PPARGPPARDPPARAALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |