Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 5/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526656 | 0.76 | — | — | |
| SCHEMBL6965549 | 0.72 | — | — | |
| SCHEMBL3186288 | 0.71 | ADAM17 (0.33) | ADAM17MMP2MMP8MMP13MMP7 | |
| SCHEMBL10652370 | 0.70 | CYP3A4 (0.38) | — | |
| SCHEMBL8571372 | 0.69 | — | — | |
| SCHEMBL8565475 | 0.69 | — | — | |
| SCHEMBL8565478 | 0.69 | — | — | |
| SCHEMBL559215 | 0.68 | — | — | |
| SCHEMBL7701584 | 0.68 | L3MBTL1 (0.39) | — | |
| SCHEMBL11902638 | 0.68 | ADAM17 (0.31) | ADAM17MMP2MMP8MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586393-B1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |