Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.52 |
| ▸ | PDE4A | P27815 | 6/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571347 | 0.93 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4CNPC1 | |
| SCHEMBL8570416 | 0.91 | PDE4D (0.52) | PDE4DPDE4APDE4BPDE4CNPC1 | |
| SCHEMBL8575066 | 0.87 | PDE4A (0.58) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL8574171 | 0.86 | PDE4A (0.45) | PDE4DPDE4APDE4BPDE4CNPC1 | |
| SCHEMBL1553391 | 0.84 | PDE4A (0.58) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8571356 | 0.83 | PDE4A (0.57) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8570003 | 0.82 | PDE4A (0.46) | PDE4DPDE4APDE4BPDE4CNPC1 | |
| SCHEMBL1553518 | 0.82 | PDE4A (0.59) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7361900 | 0.82 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8570990 | 0.81 | SMN1; SMN2 (0.43) | PDE4DPDE4APDE4BPDE4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |