Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571527 | 0.93 | PRMT5 (0.53) | ALDH1A1MAPTPRMT5WDR77MAOB | |
| SCHEMBL8575373 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTPRMT5WDR77MAOB | |
| SCHEMBL8572411 | 0.89 | MAOB (0.42) | ALDH1A1MAPTMAOBMAOACYP2C9 | |
| SCHEMBL16393547 | 0.89 | MAOB (0.42) | ALDH1A1MAPTMAOBMAOACYP2D6 | |
| SCHEMBL8571525 | 0.89 | GRM2 (0.40) | ALDH1A1MAOBMAOAGRM2POLB | |
| SCHEMBL14696869 | 0.84 | MAOB (0.47) | ALDH1A1MAOBMAOAGRM2LMNA | |
| SCHEMBL13263370 | 0.83 | MAOB (0.59) | ALDH1A1MAPTMAOBMAOASLC6A9 | |
| SCHEMBL8570451 | 0.81 | MAOB (0.39) | MAOBMAOAGRM2KMT2ALMNA | |
| SCHEMBL2401271 | 0.77 | F10 (0.51) | ALDH1A1MAOBMAOAGRM2LMNA | |
| SCHEMBL2401267 | 0.77 | F10 (0.51) | ALDH1A1MAOBMAOAGRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837870-A | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-17 | — | — | US | claimed |