Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CALML3 | P27482 | 1/20 | 0.36 |
| ▸ | SDHA | P31040 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571525 | 0.89 | GRM2 (0.40) | MAOBGRM2P2RX7MAOALMNA | |
| SCHEMBL8572411 | 0.82 | MAOB (0.42) | MAOBGRM2MAOAKMT2ALMNA | |
| SCHEMBL14696869 | 0.82 | MAOB (0.47) | MAOBGRM2P2RX7MAOALMNA | |
| SCHEMBL16393547 | 0.82 | MAOB (0.42) | MAOBGRM2P2RX7MAOALMNA | |
| SCHEMBL8570379 | 0.81 | ALDH1A1 (0.42) | MAOBGRM2MAOAKMT2ALMNA | |
| SCHEMBL8571527 | 0.81 | PRMT5 (0.53) | MAOBMAOAKMT2A | |
| SCHEMBL8575373 | 0.81 | ALDH1A1 (0.46) | MAOBMAOAKMT2ALMNAPTGS1 | |
| SCHEMBL28411961 | 0.77 | GRM2 (0.46) | MAOBGRM2P2RX7MAOALMNA | |
| SCHEMBL2401267 | 0.76 | F10 (0.51) | MAOBGRM2P2RX7MAOALMNA | |
| SCHEMBL2401271 | 0.76 | F10 (0.51) | MAOBGRM2P2RX7MAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837870-A | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-17 | — | — | US | claimed |