Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969660 | 1.00 | CASR (0.47) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL7476692 | 0.86 | CASR (0.45) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL3969657 | 0.82 | CASR (0.47) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL2638179 | 0.82 | CASR (0.47) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL17150937 | 0.82 | CASR (0.50) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL30112409 | 0.82 | CASR (0.50) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL4824743 | 0.79 | HPGD (0.51) | CASRHPGDHTR1ANISCHGAA | |
| Hydrochloric Acid SCHEMBL9153498 | 0.79 | HPGD (0.48) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL4566586 | 0.78 | CASR (0.44) | CASRHPGDHTR1ANISCHGAA | |
| SCHEMBL9701396 | 0.78 | CASR (0.56) | CASRHPGDHTR1ANISCHCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |