Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569387 | 0.81 | ALDH1A1 (0.42) | CASRHTR1ANISCHHPGDHRH3 | |
| SCHEMBL8569392 | 0.81 | ALDH1A1 (0.42) | CASRHTR1ANISCHHPGDHRH3 | |
| SCHEMBL8569391 | 0.81 | ALDH1A1 (0.42) | CASRHTR1ANISCHHPGDHRH3 | |
| SCHEMBL2638179 | 0.78 | CASR (0.47) | CASRHTR1ANISCHHPGDUSP2 | |
| SCHEMBL17150937 | 0.78 | CASR (0.50) | CASRHTR1ANISCHHPGDGAA | |
| SCHEMBL8570483 | 0.78 | CASR (0.47) | CASRHTR1ANISCHHPGDUSP2 | |
| SCHEMBL3969657 | 0.78 | CASR (0.47) | CASRHTR1ANISCHHPGDUSP2 | |
| SCHEMBL3969660 | 0.78 | CASR (0.47) | CASRHTR1ANISCHHPGDUSP2 | |
| SCHEMBL30112409 | 0.78 | CASR (0.50) | CASRHTR1ANISCHHPGDGAA | |
| SCHEMBL4824743 | 0.75 | HPGD (0.51) | CASRHTR1ANISCHHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304684-A1 | Process for the preparation of benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-03-01 | — | — | EP | claimed |
| WO-2009148659-A2 | ANTIMALARIAL QUINOLINES AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2009-12-10 | — | — | WO | disclosed |