Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077544 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL29713757 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL8572560 | 0.82 | TSHR (0.39) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL8573144 | 0.82 | ADORA3 (0.62) | MAPTNPC1RAB9APKMADORA3 | |
| SCHEMBL8569577 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL15077769 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL5335555 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL24491036 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL5336389 | 0.76 | CCNE1 (0.57) | ALDH1A1KMT2AMEN1CCNE1CDK2 | |
| SCHEMBL23966912 | 0.76 | CCNE1 (0.48) | ALDH1A1KMT2AMEN1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |