Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072263 | 0.79 | FFAR1 (0.32) | BHMTALDH1A1RENACE | |
| SCHEMBL4270562 | 0.78 | — | — | |
| SCHEMBL6035097 | 0.77 | SLC22A6 (0.50) | ALDH1A1SLC22A6TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL2066730 | 0.77 | SLC22A6 (0.50) | ALDH1A1SLC22A6TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL14346068 | 0.77 | SLC22A6 (0.50) | ALDH1A1SLC22A6TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL2066729 | 0.77 | SLC22A6 (0.50) | ALDH1A1SLC22A6TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL27533253 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL28916647 | 0.76 | TDP1 (0.48) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL20788028 | 0.75 | FOLH1 (0.43) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL9549622 | 0.75 | TDP1 (0.41) | TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828741-A1 | SPIROCYCLIC AND BICYCLIC DIAZINYL AND CARBAZINYL OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |