Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 6/20 | 0.65 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.63 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 4/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.60 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.60 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 1/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.60 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898255 | 0.89 | P2RY12 (0.65) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL5545796 | 0.89 | P2RY12 (0.69) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL8328071 | 0.88 | P2RY12 (0.64) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL2990779 | 0.88 | P2RY12 (0.66) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL3193571 | 0.88 | P2RY12 (0.68) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL8916648 | 0.88 | P2RY12 (0.70) | P2RY12DNPH1TAS1R3TAS1R1P2RY2 | |
| SCHEMBL1933421 | 0.87 | P2RY12 (0.67) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL4997219 | 0.87 | P2RY12 (0.69) | P2RY12EZH2DNPH1TAS1R3TAS1R1 | |
| SCHEMBL2988353 | 0.86 | P2RY12 (0.68) | P2RY12DNPH1TAS1R3TAS1R1P2RY2 | |
| SCHEMBL2990348 | 0.86 | P2RY12 (0.68) | P2RY12DNPH1TAS1R3TAS1R1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798240-A | ISOLATED NUCLEIC ACID ENCODING AMINOACYL-TRANSFER RNA SYNTHETASE | CUBIST PHARMACEUTICALS, INC. (US) | 1998-08-25 | — | — | US | disclosed |