Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAS2R8 | Q9NYW2 | 11/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204904 | 0.75 | TDP1 (0.65) | TDP1ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL18742872 | 0.64 | — | — | |
| SCHEMBL314480 | 0.63 | — | — | |
| SCHEMBL7567498 | 0.63 | F2 (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL96070 | 0.63 | — | — | |
| SCHEMBL8846019 | 0.62 | TNF (0.33) | — | |
| SCHEMBL7981346 | 0.62 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL15814506 | 0.61 | BRD4 (0.73) | TDP1TSHRHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL2056168 | 0.61 | — | — | |
| SCHEMBL18535556 | 0.60 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10231285-A | — | — | None | — | — | JP | disclosed |
| JP-H10231285-A | PHTHALIMIDE DERIVATIVE OR ITS SALT, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1998-09-02 | — | — | JP | disclosed |