Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 11/20 | 0.44 |
| ▸ | TP53 | P04637 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483964 | 0.97 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8573370 | 0.84 | BRD4 (0.47) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8571431 | 0.81 | BRD4 (0.47) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8573335 | 0.79 | HTR1F (0.44) | MAPTALDH1A1TP53LMNA | |
| SCHEMBL8582744 | 0.79 | KCNK3 (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8580172 | 0.79 | HTR1F (0.43) | MAPTNPC1RAB9A | |
| SCHEMBL8567836 | 0.78 | PRMT5 (0.48) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8603866 | 0.78 | KMT2A (0.45) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8568716 | 0.78 | ITK (0.39) | ALDH1A1HPGDITKHTTRECQL | |
| SCHEMBL8573391 | 0.77 | MAPT (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006402-A1 | TREATMENT OF THE COMMON COLD OR ALLERGIC RHINITIS | ELI LILLY AND COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |