Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570376 | 0.84 | MAPK1 (0.62) | RECQLL3MBTL1MAPK1MAPTALDH1A1 | |
| SCHEMBL8570374 | 0.80 | MAPK1 (0.71) | RECQLL3MBTL1MAPK1MAPTALDH1A1 | |
| SCHEMBL5293998 | 0.76 | KMT2A (0.47) | RECQLALDH1A1KMT2ACYP2C19TP53 | |
| SCHEMBL2149188 | 0.75 | ALDH1A1 (0.45) | L3MBTL1MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5558972 | 0.75 | HPGD (0.60) | RECQLMAPK1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3354467 | 0.73 | POLB (0.41) | RECQLMAPK1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14199038 | 0.72 | POLB (0.41) | RECQLL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL15157087 | 0.70 | KMT2A (0.45) | RECQLL3MBTL1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL9715954 | 0.69 | POLB (0.39) | RECQLL3MBTL1MAPK1ALDH1A1KMT2A | |
| SCHEMBL5282646 | 0.68 | KMT2A (0.42) | RECQLL3MBTL1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |