Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813722 | 0.83 | SCN1A (0.46) | SLC6A2SLC6A4TSHRIDO1TDO2 | |
| SCHEMBL8568338 | 0.80 | HTR2A (0.36) | SLC6A2SLC6A4TSHRSLC6A3KCNH2 | |
| SCHEMBL8571623 | 0.78 | TSHR (0.37) | SLC6A2SLC6A4TSHRSLC6A3KCNH2 | |
| SCHEMBL2701320 | 0.76 | CHRNB2 (0.50) | TACR1SLC6A2SLC6A4CACNA1CSLC6A3 | |
| SCHEMBL14936044 | 0.76 | GSR (0.46) | SLC6A2SLC6A4ALDH1A1TSHRCACNA1C | |
| SCHEMBL18078672 | 0.75 | TAAR1 (0.42) | TACR1SLC6A2SLC6A4TSHRCACNA1C | |
| SCHEMBL7868183 | 0.75 | SLC6A2 (0.35) | TACR1SLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL893601 | 0.75 | PDPK1 (0.44) | — | |
| SCHEMBL5642476 | 0.75 | PDPK1 (0.44) | — | |
| SCHEMBL5640880 | 0.75 | PDPK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728641-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1998-03-17 | — | — | US | disclosed |
| US-5556821-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |