Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.61 |
| ▸ | CCND1 | P24385 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629560 | 0.94 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL29433250 | 0.94 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL3393616 | 0.81 | CDK4 (0.49) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL1460648 | 0.80 | CDK4 (0.61) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL3595410 | 0.78 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL29372496 | 0.78 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL2512199 | 0.77 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL11366447 | 0.76 | CDK4 (1.00) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| Iodide SCHEMBL2581030 | 0.76 | CDK4 (0.73) | CDK4CCND1HTR2AHTR2CMAPK1 | |
| SCHEMBL25798842 | 0.76 | CDK4 (0.45) | CDK4CCND1HTR2AHTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721267-A | ANTICANCER AGENTS | SYNTEX (U.S.A.) INC. (US) | 1998-02-24 | — | — | US | disclosed |