Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.49 |
| ▸ | CCND1 | P24385 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616727 | 0.84 | CDK4 (0.52) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL29433250 | 0.83 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL1629560 | 0.83 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CKMT2A | |
| Dimethylamine SCHEMBL8570899 | 0.81 | CDK4 (0.61) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL3365353 | 0.81 | CDK4 (0.43) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL29376741 | 0.74 | CDK4 (0.67) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL3394303 | 0.74 | CDK4 (0.67) | CDK4CCND1HTR2AHTR2CKMT2A | |
| Naphthalene SCHEMBL10831150 | 0.73 | ALOX12 (0.42) | KMT2AHTTGAASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28421887 | 0.73 | CDK4 (0.64) | CDK4CCND1HTR2AHTR2CKMT2A | |
| SCHEMBL7198956 | 0.71 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121601-B1 | NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS | Université Joseph Fourier (FR) | 2016-06-15 | — | — | EP | disclosed |
| US-8343964-B2 | Indolic derivatives, their preparation processes and their uses in particular as antibacterials | UNIVERSITE JOSEPH FOURIER (FR) | 2013-01-01 | — | — | US | disclosed |
| US-20100144726-A1 | NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS | UNIVERSITE JOSEPH FOURIER (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144726-A1 | NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS | GPBAR1, TPH1, GPER1 | CDK4 2529/4885CCND1 1259/4885HTR2A 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.