Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 4/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574977 | 0.89 | HDAC11 (0.45) | RARBRARARARGHDAC7HDAC2 | |
| SCHEMBL6373222 | 0.89 | RARA (0.47) | RARBEPHX2RARARARGHDAC3 | |
| SCHEMBL8572597 | 0.83 | HIF1A (0.48) | RARBEPHX2RARARARGHDAC3 | |
| SCHEMBL6374496 | 0.82 | RARA (0.51) | RARBRARARARGHDAC7HDAC2 | |
| SCHEMBL8569004 | 0.81 | IKBKB (0.52) | RARBRARARARGHDAC7HDAC2 | |
| SCHEMBL8658216 | 0.80 | HDAC11 (0.35) | RARBRARARARGHDAC7HDAC2 | |
| SCHEMBL8658213 | 0.80 | IKBKB (0.40) | RARBRARARARGHDAC7HDAC2 | |
| SCHEMBL5888301 | 0.74 | RARB (0.57) | RARBEPHX2RARARARGHDAC3 | |
| SCHEMBL8613892 | 0.74 | MEN1 (0.41) | RARBRARARARGHDAC3HDAC4 | |
| SCHEMBL6378001 | 0.73 | RARA (0.65) | RARBRARARARGKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |
| US-5574036-A | Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1996-11-12 | — | — | US | disclosed |