Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | RARG | P13631 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618895 | 0.83 | ERN1 (0.44) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL6373222 | 0.77 | RARA (0.47) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL8569797 | 0.75 | RARA (0.46) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL6378001 | 0.74 | RARA (0.65) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL8570900 | 0.74 | RARB (0.40) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL8567746 | 0.72 | RARA (0.47) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL8572597 | 0.71 | HIF1A (0.48) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL549446 | 0.70 | MEN1 (0.73) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL8567748 | 0.70 | RARB (0.47) | MEN1KMT2ARARBRARARARG | |
| SCHEMBL3755595 | 0.68 | MEN1 (0.55) | MEN1KMT2APOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854710-A2 | USE OF A $g(g)-RAR-SPECIFIC AGONIST LIGAND TO INCREASE APOPTOSIS RATE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-07-29 | — | — | EP | claimed |
| WO-1997013505-A2 | USE OF A η-RAR-SPECIFIC AGONIST LIGAND TO INCREASE APOPTOSIS RATE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-04-17 | — | — | WO | claimed |
| EP-0854710-A2 | USE OF A $g(g)-RAR-SPECIFIC AGONIST LIGAND TO INCREASE APOPTOSIS RATE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-07-29 | — | — | EP | disclosed |
| EP-0679631-B1 | Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997013505-A2 | USE OF A η-RAR-SPECIFIC AGONIST LIGAND TO INCREASE APOPTOSIS RATE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-04-17 | — | — | WO | disclosed |
| EP-0679631-A1 | Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-11-02 | — | — | EP | disclosed |