Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571135 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL8576193 | 0.89 | MTNR1A (0.69) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL8573031 | 0.87 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL8575242 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL3914252 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL30692247 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL13888117 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL4749622 | 0.84 | MTNR1A (0.63) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL14005904 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL8570951 | 0.81 | MTNR1A (0.62) | MTNR1AMTNR1BTDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760071-A | AN UREA OR THIOUREA COMPOUNDS FOR TREATING MELATONINERGIC SYSTEM DISORDER, SLEEP DISORDER | ADIR ET COMPAGNIE (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5731352-A | THERAPY FOR DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-03-24 | — | — | US | disclosed |