Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146323 | 0.81 | TSHR (0.67) | TSHRKDM4EPOLBCA1IDO1 | |
| SCHEMBL9558574 | 0.80 | FFAR1 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL10338805 | 0.80 | IDO1 (0.46) | KDM4EPOLBIDO1ALDH1A1CA2 | |
| SCHEMBL10360966 | 0.79 | ALDH1A1 (0.46) | TSHRKDM4EPOLBALDH1A1TACR1 | |
| SCHEMBL8570364 | 0.79 | TSHR (0.64) | TSHRKDM4EPOLBCA1IDO1 | |
| SCHEMBL11452375 | 0.78 | TSHR (0.56) | TSHRKDM4EPOLBCA1IDO1 | |
| SCHEMBL14406402 | 0.78 | CA1 (0.41) | TSHRCA1IDO1ALDH1A1CA2 | |
| SCHEMBL2398930 | 0.78 | TSHR (0.50) | TSHRKDM4EPOLBCA1IDO1 | |
| SCHEMBL21408338 | 0.77 | KDM4E (0.78) | TSHRKDM4EPOLBCA1IDO1 | |
| SCHEMBL1691827 | 0.77 | TSHR (0.61) | TSHRKDM4EPOLBCA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5728641-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |