Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456525 | 0.84 | MAP4K1 (0.43) | POLBCES2CES1HTTKMT2A | |
| SCHEMBL31233534 | 0.84 | POLB (0.36) | POLBCES2CES1TDP1ERN1 | |
| SCHEMBL7456518 | 0.81 | CES2 (0.41) | POLBCES2CES1ERN1SMN1; SMN2 | |
| SCHEMBL12837479 | 0.81 | POLB (0.41) | POLBCES2CES1TDP1ERN1 | |
| SCHEMBL27248180 | 0.80 | MLYCD (0.41) | POLBCES2CES1TDP1CA1 | |
| SCHEMBL8569018 | 0.80 | TDP1 (0.58) | POLBCES2CES1TDP1ERN1 | |
| SCHEMBL8571933 | 0.80 | CA1 (0.52) | POLBCES2CES1ERN1ALDH1A1 | |
| SCHEMBL30514277 | 0.79 | KMT2A (0.53) | POLBTDP1ERN1ALDH1A1HPGD | |
| SCHEMBL7462253 | 0.77 | CES2 (0.41) | POLBCES2CES1ERN1ALDH1A1 | |
| SCHEMBL8574187 | 0.75 | MEN1 (0.51) | POLBERN1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |