SCHEMBL8572305

SCHEMBL8572305

O=C1[N]C(=O)c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5154536 0.69
SCHEMBL8369799 0.67 CA1 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5872482 0.65 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL321124 0.64
SCHEMBL7174935 0.64
SCHEMBL14157195 0.64
SCHEMBL14157108 0.64
SCHEMBL12887874 0.64
SCHEMBL247367 0.64
SCHEMBL8172999 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6192171-A None JP disclosed
US-5773236-A FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS MOLECULE PROBES, INC. (US) 1998-06-30 US disclosed
JP-H06192171-A PREPARATION OF 3-HYDROXY-2,4-5-TRIFLUOROBENZOIC ACID OCCIDENTAL CHEM CORP 1994-07-12 JP disclosed
US-4585732-A MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed