SCHEMBL5872482

SCHEMBL5872482

O=C1c2c(F)c(F)c(F)c(F)c2-c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369799 0.96 CA1 (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13779352 0.81 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9619705 0.78 KDM4E (0.34) MAPT
SCHEMBL321124 0.78
SCHEMBL12887874 0.78
SCHEMBL23198973 0.76 KDM4E (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL497324 0.74 CSNK2A2 (0.54) NPC1ALDH1A1LMNATP53POLB
SCHEMBL12110311 0.74 NQO1 (0.42) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL9619698 0.74 THRB (0.70) CA12CA1CA2CA7NPC1
SCHEMBL13640838 0.74 ADORA2A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194547-A1 THERMOELECTRIC CONVERSION MATERIAL, THERMOELECTRIC CONVERSION ELEMENT, ARTICLE FOR THERMOELECTRIC POWER GENERATION AND POWER SUPPLY FOR SENSOR FUJIFILM CORPORATION (JP) 2017-07-06 US disclosed
US-20170194547-A1 THERMOELECTRIC CONVERSION MATERIAL, THERMOELECTRIC CONVERSION ELEMENT, ARTICLE FOR THERMOELECTRIC POWER GENERATION AND POWER SUPPLY FOR SENSOR FUJIFILM CORPORATION (JP) 2017-07-06 US disclosed
US-9660166-B2 Thermoelectric conversion material, thermoelectric conversion element, article for thermoelectric power generation and power supply for sensor FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9660166-B2 Thermoelectric conversion material, thermoelectric conversion element, article for thermoelectric power generation and power supply for sensor FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-20160099397-A1 COMPOSITION FOR FORMING THERMOELECTRIC CONVERSION LAYER, THERMOELECTRIC CONVERSION ELEMENT, AND THERMOELECTRIC POWER GENERATING COMPONENT FUJIFILM CORPORATION (JP) 2016-04-07 US disclosed
US-20160099397-A1 COMPOSITION FOR FORMING THERMOELECTRIC CONVERSION LAYER, THERMOELECTRIC CONVERSION ELEMENT, AND THERMOELECTRIC POWER GENERATING COMPONENT FUJIFILM CORPORATION (JP) 2016-04-07 US disclosed
US-20160013390-A1 THERMOELECTRIC CONVERSION MATERIAL, THERMOELECTRIC CONVERSION ELEMENT, ARTICLE FOR THERMOELECTRIC POWER GENERATION AND POWER SUPPLY FOR SENSOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
US-20160013390-A1 THERMOELECTRIC CONVERSION MATERIAL, THERMOELECTRIC CONVERSION ELEMENT, ARTICLE FOR THERMOELECTRIC POWER GENERATION AND POWER SUPPLY FOR SENSOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
EP-1425318-B1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS VERSALIS SPA (IT) 2013-01-16 EP disclosed
US-7081505-B2 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2006-07-25 US disclosed
US-20040198934-A1 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2004-10-07 US disclosed
EP-1425318-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS Polimeri Europa S.p.A. (IT) 2004-06-09 EP disclosed
US-6596891-B1 Reaction product of fluoroorganic compound and organometallic compound ENICHEM S.P.A. (IT) 2003-07-22 US disclosed
WO-2003010210-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS POLIMERI EUROPA S.P.A. (IT) 2003-02-06 WO disclosed
EP-1013675-B1 Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins POLIMERI EUROPA SPA (IT) 2002-07-31 EP disclosed
EP-1013675-A2 Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins Enichem S.p.A. (IT) 2000-06-28 EP disclosed