SCHEMBL8572452

SCHEMBL8572452

CCC(=O)C1C(C)CC=C(C)C1(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8572455 1.00 CCR2 (0.31) CCR2ALDH1A1CYP3A4ALOX15TDP1
SCHEMBL8572809 1.00 CCR2 (0.31) CCR2ALDH1A1CYP3A4ALOX15TDP1
SCHEMBL8573026 0.87 HSD17B10 (0.33) CCR2
SCHEMBL8573032 0.87 HSD17B10 (0.33) CCR2
SCHEMBL8573029 0.87 HSD17B10 (0.33) CCR2
SCHEMBL8566351 0.81
SCHEMBL8566353 0.81
SCHEMBL8566346 0.81
SCHEMBL9386018 0.81 CCR2 (0.36) CCR2ALDH1A1
SCHEMBL2426198 0.77 ALDH1A1 (0.33) ALDH1A1CYP3A4ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676393-B1 Cyclic ketones and their use in perfumery FIRMENICH & CIE (CH) 1998-08-19 EP claimed
EP-0676393-A1 Cyclic ketones and their use in perfumery FIRMENICH SA (CH) 1995-10-11 EP claimed
EP-0676393-B1 Cyclic ketones and their use in perfumery FIRMENICH & CIE (CH) 1998-08-19 EP disclosed
EP-0676393-A1 Cyclic ketones and their use in perfumery FIRMENICH SA (CH) 1995-10-11 EP disclosed