Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038699 | 0.83 | KDM4E (0.46) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9042487 | 0.80 | — | — | |
| SCHEMBL9039639 | 0.79 | KDM4E (0.38) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9040424 | 0.78 | ESR1 (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9038893 | 0.78 | ESR1 (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9351612 | 0.74 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL30489617 | 0.74 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL4245745 | 0.74 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11374508 | 0.73 | KDM4E (0.61) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10825350 | 0.73 | KDM4E (0.61) | KDM4ELMNAESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719139-A | BACTERICIDES | ZENECA LIMITED (GB) | 1998-02-17 | — | — | US | disclosed |