Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038893 | 1.00 | ESR1 (0.39) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL8573221 | 0.78 | KDM4E (0.41) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9039639 | 0.77 | KDM4E (0.38) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9042542 | 0.76 | HTR2A (0.39) | KMT2A | |
| SCHEMBL9038699 | 0.72 | KDM4E (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL30489617 | 0.72 | KDM4E (0.39) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9351612 | 0.72 | KDM4E (0.39) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL4245745 | 0.72 | KDM4E (0.39) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9596535 | 0.66 | KDM4E (0.52) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9791394 | 0.66 | KDM4E (0.52) | ESR1CHRM1SLC6A4KCNH2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722945-A1 | 9-oxo-1-azabicyclo(5.2.0)non-2,3-diene-2-carboxylic acid derivatives as antibiotics | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |