Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222741 | 1.00 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9230387 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1208686 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14926712 | 0.87 | KDM4E (0.63) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14926719 | 0.85 | APP (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28740973 | 0.85 | APP (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1171573 | 0.83 | APP (0.74) | ALDH1A1MAPTMEN1KMT2AAPP | |
| SCHEMBL29449851 | 0.83 | MAPT (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL79457 | 0.83 | MAPT (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27892982 | 0.83 | MAPT (0.79) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044312-A9 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044312-A1 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-11-27 | — | — | WO | disclosed |
| US-5382600-A | 3,3-diphenylpropylamines and pharmaceutical compositions thereof | PHARMACIA AKTIEBOLAG (SE) | 1995-01-17 | — | — | US | disclosed |
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |