Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574850 | 0.89 | NPC1 (0.36) | ALDH1A1RAB9AMAPT | |
| SCHEMBL8573351 | 0.82 | MAPT (0.41) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL8577131 | 0.81 | GAA (0.34) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL8574668 | 0.81 | GAA (0.36) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL8573318 | 0.79 | TRPV1 (0.40) | ALDH1A1MAPK1RAB9AMAPT | |
| SCHEMBL8573434 | 0.78 | TRPV1 (0.35) | MEN1KMT2AAURKARAB9AL3MBTL1 | |
| SCHEMBL8602557 | 0.78 | MAPK1 (0.40) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL8573315 | 0.77 | RAB9A (0.38) | ALDH1A1MAPK1MEN1KMT2ARAB9A | |
| SCHEMBL8717987 | 0.77 | CCR3 (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL8579058 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPK1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760246-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 1998-06-02 | — | — | US | disclosed |
| US-H1729-H | Method for preparing compounds employing solid phase synthesis and novel linker-resin | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |