Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.49 |
| ▸ | PDE4A | P27815 | 10/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353707 | 0.84 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7362972 | 0.84 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7371994 | 0.84 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7365297 | 0.84 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7362976 | 0.84 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7372000 | 0.83 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7359135 | 0.81 | PDE4A (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7371995 | 0.78 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8569164 | 0.77 | KMT2A (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7365287 | 0.77 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710180-A | TREATING ALLERGIC AND INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |