Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570001 | 0.91 | HSD17B10 (0.36) | STING1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL1553351 | 0.85 | PDE4A (0.38) | TAS1R3TAS1R1MEN1KMT2AHPGD | |
| SCHEMBL8574183 | 0.85 | HSD17B10 (0.39) | STING1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL8574177 | 0.83 | PDE4A (0.39) | TAS1R3TAS1R1HPGDROCK2ROCK1 | |
| SCHEMBL1553472 | 0.83 | PDE4A (0.39) | TAS1R3TAS1R1HSD17B10HPGDROCK2 | |
| SCHEMBL8571923 | 0.81 | PDE4A (0.45) | STING1HSD17B10HPGDPDE4APDE4B | |
| SCHEMBL8572847 | 0.78 | PTGDR2 (0.41) | PTGDR2MEN1KMT2ALMNA | |
| SCHEMBL8569838 | 0.77 | HSD17B10 (0.37) | STING1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL1553694 | 0.76 | PDE4D (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1553052 | 0.76 | PDE4D (0.61) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |