Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571923 | 0.87 | PDE4A (0.45) | HSD17B10STING1PDE4APDE4BPDE4C | |
| SCHEMBL8570001 | 0.86 | HSD17B10 (0.36) | HSD17B10STING1PTGDR2MEN1KMT2A | |
| SCHEMBL8574265 | 0.85 | TAS1R3 (0.37) | HSD17B10STING1PTGDR2MEN1KMT2A | |
| SCHEMBL8572847 | 0.84 | PTGDR2 (0.41) | PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL1553545 | 0.82 | PDE4A (0.41) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL8569838 | 0.82 | HSD17B10 (0.37) | HSD17B10STING1PTGDR2MEN1KMT2A | |
| SCHEMBL8571803 | 0.81 | PDE4A (0.42) | HSD17B10MEN1KMT2APDE4APDE4B | |
| SCHEMBL1554441 | 0.81 | PDE4A (0.42) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL8569939 | 0.79 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8571039 | 0.79 | TNKS (0.50) | HSD17B10STING1AMY1AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |