Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553915 | 0.84 | PDE4A (0.41) | NPSR1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8570016 | 0.83 | PDE4A (0.40) | NPSR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8570008 | 0.83 | PDE4A (0.41) | NPSR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554296 | 0.83 | PDE4A (0.41) | NPSR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8574183 | 0.82 | HSD17B10 (0.39) | HSD17B10STING1NPSR1PTGDR2PDE4A | |
| SCHEMBL8574149 | 0.82 | PDE4A (0.51) | HSD17B10STING1PDE4APDE4BPDE4C | |
| SCHEMBL8574189 | 0.81 | PDE4A (0.52) | HSD17B10STING1PDE4APDE4BPDE4C | |
| SCHEMBL2524512 | 0.81 | HSD17B10 (0.42) | HSD17B10STING1PDE4APDE4BPDE4C | |
| SCHEMBL8574115 | 0.80 | PDE4A (0.47) | HSD17B10STING1NPSR1PDE4APDE4B | |
| SCHEMBL8571583 | 0.80 | SMN1; SMN2 (0.43) | HSD17B10STING1MEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |