SCHEMBL8574337

SCHEMBL8574337

O=C(C(=O)c1ccccc1C(=O)C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 14/20 0.78
CES1 P23141 13/20 0.78
ALDH1A1 P00352 2/20 0.52
DAO P14920 1/20 0.52
TSHR P16473 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
ALOX15 P16050 1/20 0.52
AKR1C3 P42330 1/20 0.52
RAB9A P51151 1/20 0.52
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187335 0.93 CES2 (0.67) CES2CES1ALDH1A1DAOTSHR
SCHEMBL4166060 0.91 CES2 (0.64) CES2CES1ALDH1A1DAOTSHR
SCHEMBL27889066 0.91 AKR1C3 (0.68) CES2CES1ALDH1A1AKR1C3GAA
SCHEMBL27888980 0.89 CES2 (0.61) CES2CES1AKR1C3RAB9AMAPT
SCHEMBL4166039 0.89 CES2 (0.61) CES2CES1ALDH1A1DAOTSHR
Benzil SCHEMBL7142843 0.88 CES2 (1.00) CES2CES1ALDH1A1DAOTSHR
Benzil SCHEMBL28475956 0.88 CES2 (1.00) CES2CES1ALDH1A1DAOTSHR
Benzil SCHEMBL66 0.88 CES2 (1.00) CES2CES1ALDH1A1DAOTSHR
Benzil SCHEMBL9517636 0.88 CES2 (1.00) CES2CES1ALDH1A1DAOTSHR
Benzil SCHEMBL2156589 0.88 CES2 (1.00) CES2CES1ALDH1A1DAOTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310699-A Process for synthesizing bis (phenylglyoxyloyl)benzenes usable for manufacturing polyphenylquinoxaline resins INSTITUT FRANCAIS DU PETROLE (FR) 1982-01-12 US claimed
CN-109923104-A Stable poly- (imidazoles) hydroxide 西蒙弗雷泽大学 2019-06-21 CN disclosed
US-5776990-A Foamed polymer for use as dielectric material INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-07-07 US disclosed
US-4310699-A Process for synthesizing bis (phenylglyoxyloyl)benzenes usable for manufacturing polyphenylquinoxaline resins INSTITUT FRANCAIS DU PETROLE (FR) 1982-01-12 US disclosed
US-4310699-A Process for synthesizing bis (phenylglyoxyloyl)benzenes usable for manufacturing polyphenylquinoxaline resins INSTITUT FRANCAIS DU PETROLE (FR) 1982-01-12 US disclosed
US-4024067-A Processes for the preparation of bis-benzoins and bis-benzils THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-05-17 US disclosed
US-3944614-A 2,2'-Bis(phenylethynyl-5,5'-diaminobenzidine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-03-16 US disclosed