Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24697998 | 0.96 | ACHE (0.40) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL29466623 | 0.77 | MAPK1 (0.47) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL29466625 | 0.77 | ACHE (0.44) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL1819184 | 0.77 | MAPK1 (0.47) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL6457198 | 0.77 | ACHE (0.44) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL15831715 | 0.76 | MAPK1 (0.46) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL31095398 | 0.76 | MAPK1 (0.46) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL23816987 | 0.76 | MAPK1 (0.46) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL16136206 | 0.76 | MAPK1 (0.46) | ACHEMAPK1NSD2MEN1KMT2A | |
| SCHEMBL15831714 | 0.76 | ACHE (0.43) | ACHEMAPK1NSD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |