Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.35 |
| ▸ | BCHE | P06276 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574606 | 0.96 | ACHE (0.41) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL633261 | 0.77 | ACHE (0.43) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL30777931 | 0.77 | ACHE (0.43) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL30350953 | 0.77 | ACHE (0.43) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL1821069 | 0.77 | ACHE (0.43) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL13394086 | 0.74 | KDM4E (0.53) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL1586850 | 0.74 | KDM4E (0.53) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL18711586 | 0.74 | KDM4E (0.41) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL191381 | 0.74 | ACHE (0.40) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL9267023 | 0.74 | ACHE (0.50) | ACHEMAPK1MEN1KMT2ABPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |