Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572885 | 0.90 | HSD17B10 (0.47) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8574149 | 0.90 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL8574598 | 0.86 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL1552797 | 0.84 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| Hydrochloric Acid SCHEMBL8571296 | 0.83 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL8571063 | 0.82 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2524512 | 0.82 | HSD17B10 (0.42) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL8574115 | 0.81 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL1554227 | 0.81 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL8571288 | 0.81 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DRNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |