Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572885 | 0.91 | HSD17B10 (0.47) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8575103 | 0.90 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL2524512 | 0.89 | HSD17B10 (0.42) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL8574189 | 0.89 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL8570003 | 0.87 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8574598 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL8571063 | 0.85 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8574115 | 0.84 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DSTING1 | |
| SCHEMBL8569965 | 0.84 | RAB9A (0.48) | STING1HSD17B10POLB | |
| SCHEMBL8571583 | 0.84 | SMN1; SMN2 (0.43) | STING1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |