Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571546 | 0.87 | HSD17B10 (0.47) | HSD17B10GAAKDM4EHPGDALDH1A1 | |
| SCHEMBL8571583 | 0.87 | SMN1; SMN2 (0.43) | HSD17B10STING1GAAALDH1A1CAMK2A | |
| SCHEMBL8569965 | 0.87 | RAB9A (0.48) | HSD17B10STING1GAAKDM4EHPGD | |
| SCHEMBL8574149 | 0.84 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL1553428 | 0.84 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2524512 | 0.83 | HSD17B10 (0.42) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8574189 | 0.83 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8575380 | 0.83 | HSD17B10 (0.46) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8572881 | 0.83 | HSD17B10 (0.46) | HSD17B10AMY1ASTING1GAAKDM4E | |
| SCHEMBL8572885 | 0.82 | HSD17B10 (0.47) | PDE4APDE4BPDE4CPDE4DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |