Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18527316 | 0.77 | HTR2A (0.37) | HTR2AHTR2CMEN1KMT2AGRM5 | |
| SCHEMBL18527166 | 0.77 | HTR2A (0.37) | HTR2AHTR2CMEN1KMT2AGRM5 | |
| SCHEMBL29548539 | 0.72 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL669577 | 0.72 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL6025331 | 0.71 | HTR2A (0.38) | HTR2AHTR2C | |
| SCHEMBL6024522 | 0.71 | HTR2A (0.38) | HTR2AHTR2C | |
| SCHEMBL7300514 | 0.70 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL18911620 | 0.70 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL30785316 | 0.68 | GRM5 (0.36) | MEN1KMT2AGRM5 | |
| SCHEMBL24916793 | 0.68 | SIGMAR1 (0.50) | HTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756501-A | USEFUL FOR TREATING ALZHIMER'S DISEASE, DOWN'S SYNDROM AND PARKINSON'S DISEASE INVOLVING HYPOFUNCTION OF ACETYLCHOLINE IN MAMMAL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |