Sugi Predict

Sugi Predict / Compounds / SCHEMBL8575190

SCHEMBL8575190

SCHEMBL8575190

ClC(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)CCOC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 1/20 0.49
▸ DUT P33316 3/20 0.38
▸ HRH4 Q9H3N8 1/20 0.36
▸ TSHR P16473 2/20 0.33
▸ TK2 O00142 8/20 0.33
▸ CYP2C9 P11712 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ SLC6A1 P30531 1/20 0.32
▸ TK1 P04183 1/20 0.32
▸ CHRM2 P08172 1/20 0.31
▸ PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8571362 1.00 KIF11 (0.49) KIF11DUTHRH4TSHRTK2
SCHEMBL8570336 0.98 KIF11 (0.50) KIF11DUTHRH4TSHRTK2
SCHEMBL8573764 0.86 KIF11 (0.45) KIF11DUTHRH4TSHRTK2
SCHEMBL8718031 0.73 KIF11 (0.49) KIF11DUTHRH4TSHRTK2
SCHEMBL11275984 0.73 KIF11 (0.74) KIF11DUTHRH4TSHRTK2
SCHEMBL8574662 0.72 DUT (0.38) DUT
SCHEMBL8569640 0.72 DUT (0.38) DUT
SCHEMBL4653330 0.72 KIF11 (0.60) KIF11DUTHRH4TSHRTK2
SCHEMBL8720340 0.71 — —
SCHEMBL3573169 0.70 KIF11 (0.63) KIF11DUTHRH4TSHRTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 — — US disclosed