SCHEMBL8575204

SCHEMBL8575204

ClC(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP2E1 P05181 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2405628 1.00 ALDH1A1 (0.33) ALDH1A1LMNACYP2E1TSHR
SCHEMBL3535287 1.00 ALDH1A1 (0.33) ALDH1A1LMNACYP2E1TSHR
SCHEMBL6693744 1.00 ALDH1A1 (0.33) ALDH1A1LMNACYP2E1TSHR
SCHEMBL8568629 1.00 ALDH1A1 (0.33) ALDH1A1LMNACYP2E1TSHR
SCHEMBL8573008 1.00 ALDH1A1 (0.33) ALDH1A1LMNACYP2E1TSHR
SCHEMBL8445734 0.94 TSHR (0.38) ALDH1A1LMNACYP2E1TSHR
Hydrochloric Acid SCHEMBL532903 0.89
SCHEMBL8681885 0.85 MEN1 (0.36)
SCHEMBL532905 0.85
SCHEMBL532904 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed