Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576383 | 1.00 | PTPN1 (0.41) | PTPN1PTPN2PTPN6PTPN11CTSK | |
| SCHEMBL8577933 | 1.00 | PTPN1 (0.41) | PTPN1PTPN2PTPN6PTPN11CTSK | |
| SCHEMBL8577792 | 1.00 | PTPN1 (0.41) | PTPN1PTPN2PTPN6PTPN11CTSK | |
| SCHEMBL9702258 | 0.88 | PTPN1 (0.39) | PTPN1PTPN2PTPN6PTPN11TNF | |
| SCHEMBL8577949 | 0.87 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11TNF | |
| SCHEMBL15833434 | 0.87 | PTPN1 (0.48) | PTPN1PTPN2PTPN11TNFTSHR | |
| SCHEMBL8576622 | 0.87 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11TNF | |
| SCHEMBL16299427 | 0.87 | PTPN1 (0.48) | PTPN1PTPN2PTPN11TNFTSHR | |
| SCHEMBL8573455 | 0.87 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11TNF | |
| SCHEMBL17850338 | 0.86 | PTPN1 (0.49) | PTPN1PTPN2PTPN11TNFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016537-A1 | NOVEL COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-04-23 | — | — | WO | disclosed |